Parkinson hastalarında nötrofil/lenfosit oranları, C reaktif protein ve sedimantasyon hızlarının değerlendirilmesi
Yazarlar (6)
Türkiye
Türkiye
Prof. Dr. Dürdane AKSOY
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Betül ÇEVİK
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
|
| Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
| Dergi Adı | Cukurova Medical Journal |
| Dergi ISSN | 2602-3032 Wos Dergi |
| Dergi Tarandığı Indeksler | ESCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2018 |
| Cilt No | 43 |
| Sayı | 2 |
| Sayfalar | 305 / 311 |
| DOI Numarası | 10.17826/cumj.341649 |
| Makale Linki | http://dergipark.gov.tr/doi/10.17826/cumj.341649 |
| Özet |
| Purpose: Recent studies have reported increased peripheral inflammation could have an important role in the pathogenesis in Parkinson’s disease (PD). In the light of these data, we aimed to investigate the systemic inflammation status by analyzing the Neutrophil/Lymphocyte (N/L) ratio, Erythrocyte Sedimentation Rate (ESR), and C-reactive protein (CRP) in patients with PD.Material and Methods: We have taken to our study 101 PD patients, and 60 healthy subjects of similar age and gender. The demographic data and duration of the disease, the drugs, duration of usage of Parkinson drugs, Hoehn-Yahr stage were noted. After full neurological examination blood samples are collected and neutrophil, lymphocyte counts, high sensitive CRP, ESR levels are detected.Results: The N/L ratio and the CRP levels were statistically higher in Parkinson’s group. There was a statistically significant but weak positive correlation between the CRP levels and the N/L ratio with the disease duration. Similarly, there was a statistically significant but weak positive correlation between the CRP levels and the N/L ratios with Hoehn-Yahr stages. When the N/L rates of the Parkinson's patients were correlated with the CRP and the ESR levels separately, it was observed that there was a weak but statistically significant correlation between the CRP and the N/L ratioConclusion: We found that the N/L ratio, and CRP levels, which are very important indicators of peripheral inflammation, was higher in PD. Our findings suggest that these biochemical markers may have a predictive value for the diagnosis of PD.Amaç: Son yıllarda yapılan çalışmalar artmış periferik … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 4 |