Lead nitrate induced oxidative stress in brain tissues of rats Protective effect of sodium selenite
Yazarlar (4)
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
Dr. Öğr. Üyesi Filiz DEMİR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Bozok Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Gazi University Journal of Science |
| Dergi ISSN | 2147-1762 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2014 |
| Cilt No | 27 |
| Sayı | 3 |
| Sayfalar | 883 / 889 |
| Özet |
| Lead used in many industrial applications and it has been recognized as a toxic metal. The aim of this study is to investigate the effects of lead nitrate on brain tissues of diabetic and non-diabetic rats and the protective role of sodium selenite. Four weeks later, changes in antioxidant enzyme activities and MDA levels determined in the brain tissues. At the end of the study, we showed that lead nitrate causes oxidative stress in diabetic and non-diabetic rat brain and the sodium selenite can ameliorate this toxicity, but not protect completely. |
| Anahtar Kelimeler |
| Antioxidant enzymes | Brain | Lead nitrate | Oxidative stress | Sodium selenite |
