Effects of sodium selenite supplementation on lead nitrate induced oxidative stress in lung tissue of diabetic and non diabetic rats
Yazarlar (4)
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
Dr. Öğr. Üyesi Filiz DEMİR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Bozok Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayınlanan tam makale |
| Dergi Adı | Gazi University Journal of Science |
| Dergi ISSN | 2147-1762 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | EBSCO |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2014 |
| Cilt No | 27 |
| Sayı | 2 |
| Sayfalar | 847 / 853 |
| Özet |
| In this study, diabetic and non-diabetic male rats were given to sodium selenite, lead nitrate and sodium selenite plus lead nitrate through gavage. At the end of the 4th week, lipid peroxidation and antioxidant enzyme activities were investigated compared to control group. No significant differences were observed between control and sodium selenite treated groups. By the end of the fourth week, lead nitrate led to increase the levels of MDA, and decrease in antioxidant enzyme activities compared with the control group in diabetic and nondiabetic rats. As a result, sodium selenite significantly reduces lead nitrate induced lung toxicity in diabetic and non-diabetic groups. |
| Anahtar Kelimeler |
| Diabetes | Lead nitrate | Lung | Oxidative stress | Sodium selenite |
