A review on the synthesis and applications of molecules as anticonvulsant drug agent candidates       
Yazarlar (2)
Doç. Dr. Oğuz ÖZBEK Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Prof. Dr. Meliha Burcu GÜRDERE Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Medicinal Chemistry Research
Dergi ISSN 1054-2523 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 09-2020
Cilt No 29
Sayı 9
Sayfalar 1553 / 1578
DOI Numarası 10.1007/s00044-020-02595-4
Makale Linki https://doi.org/10.1007/s00044-020-02595-4
Özet
Epilepsy is one of the most common neurological disorders worldwide and it requires a long-term or life-long treatment. Current standard treatment includes the use of antiepileptic drugs. To date, many organic compounds have been synthesized by chemists as potential antiepileptic drugs and their anticonvulsant properties have been investigated. While evaluating the anticonvulsant activities of these newly synthesized molecules, known antiepileptic drugs are used as reference. Thus, many novel molecules with anticonvulsant properties have been added to the literature. It is clear that these new molecules will be effective in the treatment of epilepsy. In this review, we investigated the synthesis and properties of organic compounds with anticonvulsant properties.
Anahtar Kelimeler
Anticonvulsant activity | Antiepileptic drug | Epilepsy | Synthesis