Estimation of Median Values of Second Trimester Screening Test for Our Hospital      
Yazarlar (1)
Doç. Dr. Muzaffer KATAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale
Dergi Adı International Journal of Medical Biochemistry
Dergi ISSN 2587-2362 Scopus Dergi
Dergi Tarandığı Indeksler TUBITAK TR Index, Turk Medline, CNKI. ProQuest, COPE, CABI, EBSCO, Crossref
Makale Dili İngilizce
Basım Tarihi 01-2020
Cilt No 3
Sayı 1
Sayfalar 29 / 37
DOI Numarası 10.14744/ijmb.2019.22932
Makale Linki http://www.internationalbiochemistry.com/jvi.aspx?un=IJMB-22932
Özet
Objectives: The aim of this study was to determine the median values of the maternal serum triple screen test components,beta human chorionic gonadotropin (β-hCG), alpha-fetoprotein (AFP), and unconjugated estriol (uE3), at a singlehospital in order to enhance prenatal diagnostic ability and to report fetal anomaly risks more accurately and reliably.Methods: The triple test results of 692 pregnant women were evaluated retrospectively. The median values specific toa single laboratory were determined and compared with those of a fetal risk assessment software program.Results: The laboratory estimated β-hCG medians according to gestational week were higher than those of the 14thand 16th week generated by the software program and lower in the other weeks. The serum estimated medians for AFPwere higher than those of the program in all weeks except the 14th week. The difference between weeks 15, 16, and 17was significant (p<0.001). For uE3, the estimated medians were lower than the software results and the difference wassignificant at weeks 15, 16, 17, and 18 (p<0.001).Conclusion: The determination of regional median values would provide more accurate and reliable results for prenatalscreening tests.
Anahtar Kelimeler
Alpha-fetoprotein | beta human chorionic gonadotropin | median | second trimester | unconjugated estriol
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
TRDizin 1
Google Scholar 4
Estimation of Median Values of Second Trimester Screening Test for Our Hospital

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