Investigation of ICAM-1 levels in hypertensive patients with fragmented QRS complexes      
Yazarlar (8)
Lütfü Bekar
Hitit Üniversitesi, Türkiye
Macit Kalçık
Hitit Üniversitesi, Türkiye
Doç. Dr. Muzaffer KATAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Mucahit Yetim
Hitit Üniversitesi, Türkiye
Oğuzhan Çelik
Muğla Sıtkı Koçman Üniversitesi, Türkiye
Tolga Doğan
Hitit Üniversitesi, Türkiye
Yusuf Karavelioğlu
Hitit Üniversitesi, Türkiye
Zehra Gölbaşı
Hitit Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Acta Cardiologica
Dergi ISSN 0001-5385 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 04-2020
Cilt No 75
Sayı 2
Sayfalar 123 / 129
DOI Numarası 10.1080/00015385.2018.1555200
Makale Linki https://www.tandfonline.com/doi/full/10.1080/00015385.2018.1555200
Özet
Objective: Fragmented QRS (fQRS) detected on a 12-lead electrocardiogram (ECG) has been demonstrated to be a marker of myocardial fibrosis. Intercellular adhesion molecule-1 (ICAM-1) is a protein which plays an important role in fibro-inflammatory processes. In this study, we aimed to investigate the relationship between ICAM-1 levels and the presence of fQRS in hypertensive patients.Methods: Ninety consecutive patients who were diagnosed with hypertension were included in the study. ECG and transthoracic echocardiography were performed to all patients. fQRS was defined as additional R’ wave or notching/splitting of S wave in two contiguous ECG leads. Serum ICAM-1 levels were measured using the enzyme-linked immunosorbent assay method. Patients were divided into two groups according to the presence of fQRS.Results: A total of 90 patients (female, 65%; mean age: 54.6 ± 8.5 years) were …
Anahtar Kelimeler
Echocardiography | fragmented QRS complex | hypertension | inflammation | intercellular adhesion molecule | myocardial fibrosis