Determination of Median Values of First Trimester Screening Tests: A Tokat Scale Retrospective Study
Yazarlar (1)
Doç. Dr. Muzaffer KATAR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
| Dergi Adı | Van Sağlık Bilimleri Dergisi |
| Dergi ISSN | 2667-5072 |
| Dergi Tarandığı Indeksler | CAS (Chemical Abstract), CABI, IPIndexing, InfoBase Index, Türkiye Atıf Dizini, CiteFactor, SIS, J-Gate, General IF, Asos Index, JF, BASE, Google Scholar, Root Indexing, WCOSJ, ESJI, IJIFACTOR, I2OR-6263, DRJI, Copernicus |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2019 |
| Cilt No | 12 |
| Sayı | 2 |
| Sayfalar | 15 / 21 |
| Makale Linki | https://dergipark.org.tr/tr/pub/vansaglik/issue/51449/615059 |
| Özet |
| ObjectivesThe aim of this study was to determine the ability of maternal serum plasmaprotein A (PAPP-A) and free beta-human chorionic gonadotropin (free ß-hCG)values measured in the first trimester screening test to predict thecomplications that may develop in later gestational weeks, calculate the medianvalues of these parameters and compare them with those of software we use. Materials and methodsThe study included 16-46 years old women who applied to biochemistry laboratoryof Tokat Gaziosmanpasa University School of Medicine with gestational ages of 10weeks and 6 days to 13 weeks and 6 days. The results of 3166 pregnant women wereevaluated retrospectively. ResultsThe mean age of the patients was 27.43 ± 5.46 and their weight was 65.66 ±13.13 kilograms. Crown rump lengthes (CRL) were determined as 60.71 ± 8.56 mm.Free ß-hCG levels were 55.1 ± 132.07 ng / mL and PAPP-A values were 3683.53 ±2486 mIU / l. Nuchal translucency measurements (NT) were determined as 1.38 ±0.37mm. PAPP-A and Free ß-hCG MoM values were 1.23 ± 0.68 and 1.23 ± 0.88,respectively. New median values of β-hCG were found to be significantly lowerthan those of the program (p <0.05), while PAPP-A values weresignificantly higher (p <0.05).ConclusionThe accuracy and performance of first trimester screening tests should beimproved. Determination of median values specific to the region and even tothe laboratory is now inevitable |
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