Determination of Median Values of First Trimester Screening Tests: A Tokat Scale Retrospective Study
Yazarlar (1)
Doç. Dr. Muzaffer KATAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
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| Dergi Adı | Van Sağlık Bilimleri Dergisi | ||
| Dergi ISSN | 2667-5072 | ||
| Dergi Tarandığı Indeksler | CAS (Chemical Abstract), CABI, IPIndexing, InfoBase Index, Türkiye Atıf Dizini, CiteFactor, SIS, J-Gate, General IF, Asos Index, JF, BASE, Google Scholar, Root Indexing, WCOSJ, ESJI, IJIFACTOR, I2OR-6263, DRJI, Copernicus | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2019 |
| Cilt / Sayı / Sayfa | 12 / 2 / 15–21 | DOI | – |
| Makale Linki | https://dergipark.org.tr/tr/pub/vansaglik/issue/51449/615059 | ||
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| Objectives The aim of this study was to determine the ability of maternal serum plasma protein A (PAPP-A) and free beta-human chorionic gonadotropin (free ß-hCG) values measured in the first trimester screening test to predict the complications that may develop in later gestational weeks, calculate the median values of these parameters and compare them with those of software we use. Materials and methods The study included 16-46 years old women who applied to biochemistry laboratory of Tokat Gaziosmanpasa University School of Medicine with gestational ages of 10 weeks and 6 days to 13 weeks and 6 days. The results of 3166 pregnant women were evaluated retrospectively. Results The mean age of the patients was 27.43 ± 5.46 and their weight was 65.66 ± 13.13 kilograms. Crown rump lengthes (CRL) were determined as 60.71 ± 8.56 mm. Free ß-hCG levels were 55.1 ± 132.07 ng / mL and PAPP-A values were 3683.53 ± 2486 mIU / l. Nuchal translucency measurements (NT) were determined as 1.38 ± 0.37mm. PAPP-A and Free ß-hCG MoM values were 1.23 ± 0.68 and 1.23 ± 0.88, respectively. New median values of β-hCG were found to be significantly lower than those of the program (p <0.05), while PAPP-A values were significantly higher (p <0.05). Conclusion The accuracy and performance of first trimester screening tests should be improved. Determination of median values specific to the region and even to the laboratory is now inevitable |
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