Evaluation of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged
Yazarlar (5)
Prof. Dr. Fikret GEVREK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Osman Serden Gencel
T.C. Sağlık Bakanlığı
T.C. Sağlık Bakanlığı
Selim Görgün T.C. Sağlık Bakanlığı, Türkiye
Doç. Dr. Muzaffer KATAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Mikail Kara Hatay Mustafa Kemal Üniversitesi, Türkiye
| Bildiri Türü |
Tebliğ/Bildiri
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Bildiri Dili | İngilizce |
| Bildiri Alt Türü | Özet Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum) | ||
| Bildiri Niteliği | Alanında Hakemli Uluslararası Kongre/Sempozyum | ||
| Kongre Adı | 1st INTERNATIONAL CONGRESS OF HISTOLOGY AND EMBRYOLOGY | ||
| Kongre Tarihi | 26-05-2022 / 28-05-2022 | ||
| Basıldığı Ülke | Türkiye | Basıldığı Şehir | Ankara |
| Bildiri Linki | www.nichecongress.com | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups. Material and methods This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18–25 years (n= 20); group 2, age 26–35 years (n= 20); and group 3, age≥ 35 years (n= 20). Sperm ejaculates obtained from each participant were used for spermiogram tests, Kruger strict morphology analysis, and immunohistochemistry. Results We observed no statistically significant differences in terms of macroscopic and microscopic sperm testing. The immunostaining score of aquaporin-3 was the lowest in group 1 and increased in group 3 and group 2, respectively (p< 0.05). Aquaporin-8 immunostaining only increased in group 2 (p< 0.05). Aquaporin-7 immunostaining scores were not different between the groups (p> 0.05). When the immunostaining scores of aquaporin molecules were compared with each other, aquaporin-7 was significantly increased compared with the others (p< 0.05). Conclusion According to the results, it can be stated that aquaporin-3 and aquaporin-8 molecules were more expressed at age 26 to 35 years, and aquaporin-7 was densely expressed from age 18 to 25 years. If the characterization of these molecules is adversely affected, male infertility may eventually emerge. We recommend further advanced-level studies on this subject. |
| Anahtar Kelimeler |
