Microwave-assisted green synthesis of silver nanoparticles using crude extracts of Boletus edulis and Coriolus versicolor: Characterization, anticancer, antimicrobial and wound healing activities     
Yazarlar (7)
Özlem Kaplan
Istanbul Üniversitesi, Türkiye
Nazan Gökşen Tosun
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Aykut ÖZGÜR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Seçil ERDEN TAYHAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Sema BİLGİN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. İbrahim TÜRKEKUL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. İsa GÖKÇE Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Journal of Drug Delivery Science and Technology
Dergi ISSN 1773-2247 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili Türkçe
Basım Tarihi 08-2021
Cilt No 64
Sayı 1
Sayfalar 1 / 8
DOI Numarası 10.1016/j.jddst.2021.102641
Makale Linki http://dx.doi.org/10.1016/j.jddst.2021.102641
Özet
The green synthesis of metal nanoparticles has been promising approach in the field of nanomedicine due to its low-cost, non-toxic, biocompatible and sustainable features. In literature, therapeutic potentials of silver nanoparticles (AgNPs) coupled with natural extracts have been extensively evaluated against various diseases. The present study aims at preparation of AgNPs using Coriolus versicolor and Boletus edulis mushroom extract based on the microwave-assisted method. The synthesized C. versicolor-silver nanoparticles (CV-AgNPs) and B. edulis-silver nanoparticles (BE-AgNPs) were characterized by UV–Visible spectroscopy, dynamic light scattering technique (DLS) and fourier transform infrared spectroscopy (FTIR). Anticancer activity of AgNPs was tested on MCF-7, HT-29 and HUH-7 cell lines. Antimicrobial efficacy of AgNPs was determined against pathogens bacterial (Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus and Enterococcus faecalis) and fungal (Candida albicans and Candida utilis) strains. Also, wound healing potential of AgNPs was examined on L929 cells. Obtained results demonstrated that synthesized CV-AgNPs and BE-AgNPs had an average size diameter of <100 nm and have strong anticancer, antibacterial, antifungal and wound healing potentials.
Anahtar Kelimeler
Silver nanoparticles | Green synthesis | Microwave assisted | Boletus edulis | Coriolus versicolor anticancer | Antimicrobial | Wound healing