| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Movement Disorders |
| Dergi ISSN | 0885-3185 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2008 |
| Cilt No | 23 |
| Sayı | 13 |
| Sayfalar | 1947 / 1948 |
| DOI Numarası | 10.1002/mds.21911 |
| Özet |
| High-frequency stimulation of the subthalamic nucleus (STNHFS) has similar clinical effects in Parkinson’s disease (PD) as subthalamotomy but less risks. 1, 2 Surprisingly, a recent study in parkinsonian monkeys showed no inhibitory but an excitatory effect of STN-HFS on GPi neurons. 3 This discrepancy could be explained by a dual effect of STN-HFS consisting of axonal excitation while the soma becomes silenced. 4 We had the opportunity to study the impact of STN-HFS on pallidal neuronal activity in a parkinsonian patient.The 56-year-old man with a 40 year history of PD had previously undergone STN-HFS at our center5 for treating severe motor fluctuations and dyskinesias at the age of 51. Despite the unusually early onset of clinical symptoms, the patient did not carry a Parkin, PINK or DJ-1 mutation and had no family history of PD. STN-HFS (monopolar, 2 V, 180 Hz, 60 μs pulse width) was highly effective … |
| Anahtar Kelimeler |
| Dergi Adı | MOVEMENT DISORDERS |
| Yayıncı | John Wiley & Sons Inc. |
| Açık Erişim | Hayır |
| ISSN | 0885-3185 |
| E-ISSN | 1531-8257 |
| CiteScore | 13,3 |
| SJR | 2,464 |
| SNIP | 1,759 |