Synthesis and cytotoxic activities of novel 2 1 5 bis aryl penta 1 4 dien 2 yl benzo d thiazol derivatives
Yazarlar (3)
Çankırı Karatekin Üniversitesi, Türkiye
Prof. Dr. Mustafa CEYLAN
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayınlanan tam makale |
| Dergi Adı | ORGANIC COMMUNICATIONS |
| Dergi ISSN | 1307-6175 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | EBSCO |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2016 |
| Cilt No | 9 |
| Sayı | 3 |
| Sayfalar | 65 / 72 |
| Özet |
| Novel 2-(1, 5-bis (aryl) penta-1, 4-dien-2-yl) benzo [d] thiazol (5a, b) and 2-(((1S, 2S, E)-2-(benzo [d] thiazol-2-yl)-1, 5-di-arylpent-4-en-1-yl) thio) aniline (6a, b) derivatives were obtained by addition of 2-aminobenzothiol to bis-benzylidinecyclobutanones (3a, b). The structures of the obtained compounds were characterized using the spectroscopic methods (NMR, IR, Elemental Analysis). Compounds 5a, b showed cytotoxic activities against C6 (Rat Brain tumor cells) and HeLa (human uterus carcinoma) in vitro.© 2016 ACG Publications. All rights reserved. |
| Anahtar Kelimeler |
| 2-Alkylbenzothiazol | Anticancer | C6 and HeLa cell lines |
