| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Cardiovascular Journal of Africa |
| Dergi ISSN | 1995-1892 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2017 |
| Cilt No | 28 |
| Sayı | 3 |
| Sayfalar | 154 / 158 |
| DOI Numarası | 10.5830/CVJA-2016-074 |
| Makale Linki | http://cvja.co.za/onlinejournal/vol28/vol28_issue3/20/z |
| Özet |
| Background: Familial Mediterranean fever (FMF) is a chronic, recurrent auto-inflammatory disease characterised by self-Terminating attacks of fever and sterile polyserositis. The main cause of death in auto-inflammatory diseases is cardiovascular events. Additionally, auto-inflammatory diseases have potential effects on the myocardial repolarisation parameters, including the T-wave peak-To-end (Tp-Te) interval, cTp-Te interval (corrected Tp-Te) and the cTp-Te/ QT ratio. The aim of this study was to analyse the efficacy of myocardial repolarisation alterations in anticipation of cardiovascular risks in patients with FMF. Methods: This study included 66 patients with FMF and 58 healthy control subjects. Tp-Te and cTp-Te intervals and the cTp-Te/QT ratio were measured from the 12-lead electrocardiogram. Results: In electrocardiographic parameters, analysis of QT, QT dispersion, corrected QT (QTc) and QTc dispersion were similar between the groups. The Tp-Te and cTp-Te intervals and Tp-Te/QT and cTp-Te/QT ratios were significantly prolonged in FMF patients. Multivariate linear regression analyses indicated that erythrocyte sedimentation rate was an independent predictor of a prolonged cTp-Te interval. Conclusions: Our study revealed that when compared with control subjects, Tp-Te and cTp-Te intervals and cTp-Te/QT ratio were increased in FMF patients. |
| Anahtar Kelimeler |
| CTp-Te interval | CTp-Te/QT ratio | Familial mediterranean fever | Myocardial repolarisation |
| Dergi Adı | Cardiovascular Journal of Africa |
| Yayıncı | Cardiovascular Journal of South Africa |
| Açık Erişim | Hayır |
| ISSN | 1995-1892 |
| E-ISSN | 1680-0745 |
| CiteScore | 0,0 |
| SJR | 0,265 |
| SNIP | 0,291 |