Red Cell Distribution Width is Correlated With Extensive Coronary Artery Disease in Patients With Diabetes Mellitus      
Yazarlar (8)
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Metin KARAYAKALI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fatih Altunkaş
Türkiye
Doç. Dr. Kayıhan KARAMAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Arif Arısoy
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Köksal Ceyhan
Türkiye
Hasan Kadı
Balıkesir Üniversitesi, Türkiye
Fatih Koç
Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Cardiovascular Journal of Africa
Dergi ISSN 1995-1892 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 10-2017
Cilt No 28
Sayı 5
Sayfalar 319 / 323
DOI Numarası 10.5830/CVJA-2017-015
Makale Linki http://cvja.co.za/onlinejournal/vol28/vol28_issue5/45/z
Özet
Introduction: Previous studies have predicted an independent relationship between red cell distribution width (RDW) and the risk of death and cardiovascular events in patients with coronary artery disease (CAD). The aim of this study was to investigate the relationship between RDW and extensiveness of CAD in patients with diabetes mellitus (DM). Methods: Two hundred and thirty-three diabetic patients who underwent coronary angiographies at our centre in 2010 were included in the study. All of the angiograms were re-evaluated and Gensini scores were calculated. Triple-vessel disease was diagnosed in the presence of stenosis > 50% in all three coronary artery systems. Result: RDW was significantly higher in diabetic CAD patients (p < 0.001). Patients with CAD who had a RDW value above the cut-off point also had higher Gensini scores, higher percentages of obstructive CAD and triple-vessel disease (p ≤ 0.001 for all). According to the cut-off values calculated using ROC analysis, RDW > 13.25% had a high diagnostic accuracy for predicting CAD. RDW was also positively correlated with Gensini score, obstructive CAD and triple-vessel disease (r < 0.468 and p < 0.001 for all). Conclusion: RDW values were found to be increased in the diabetic CAD population. Higher RDW values were related to more extensive and complex coronary lesions in patients with DM.
Anahtar Kelimeler
Coronary artery disease | Diabetes mellitus | Gensini score | Red cell distribution width