Association of sleep apnea with coronary slow flow phenomenon      
Yazarlar (10)
Ozcan Ozeke
Acıbadem Mehmet Ali Aydınlar Üniversitesi, Türkiye
Mutlu Gungor
Bayindir Hospital, Türkiye
Cagatay Ertan
Acıbadem Mehmet Ali Aydınlar Üniversitesi, Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dilek Aydin
Bayindir Hospital, Türkiye
Ozcan Erturk
Bayindir Hospital, Türkiye
Serap B. Hizel
Bayindir Hospital, Türkiye
Fuat Ozgen
Bayindir Hospital, Türkiye
Ahmet D. Demir
Acıbadem Mehmet Ali Aydınlar Üniversitesi, Türkiye
Can Ozer
Bayindir Hospital, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı JOURNAL OF CARDIOVASCULAR MEDICINE
Dergi ISSN 1558-2027 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2012
Cilt No 13
Sayı 6
Sayfalar 376 / 380
DOI Numarası 10.2459/JCM.0b013e3283528f14
Özet
BACKGROUND: Both obstructive sleep apnea (OSA) and coronary slow-flow phenomenon (CSFP) are known to share similar etiopathogenic mechanisms, such as chronic sympathetic activation, upregulation of inflammatory pathways, oxidative stress and, finally, endothelial dysfunction. OBJECTIVE: We evaluated whether there is an association between OSA and coronary flow rates. METHOD: We retrospectively reviewed medical records of all patients who underwent diagnostic nocturnal polysomnography for suspected OSA. Those who had coronary angiography performed within the same year of polysomnography were divided into two main groups: those with (group 1) and without (group 2) OSA; also, angiographic coronary TIMI (thrombolysis in myocardial infarction) frame counts (TFC) were compared between the groups. Patients with coronary arterial stenosis and angiograms with inadequate filling of the coronary arteries or visualization of the distal landmarks for frame counting were excluded from the study. RESULTS: There was a statistically significant difference between the groups regarding TFCs. We found a significant positive correlation between mean TFC and apnea-hypopnea index (r = 0.611, P < 0.001). CONCLUSION: The current study demonstrated that sleep apnea impairs coronary flow rates and is associated with CSFP. © 2012 Italian Federation of Cardiology.
Anahtar Kelimeler
sleep apnea | slow coronary flow | TIMI frame count
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 3
Google Scholar 14
Association of sleep apnea with coronary slow flow phenomenon

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