Frequency of fragmented QRS on ECG is increased in patients with rheumatoid arthritis without cardiovascular disease a pilot study      
Yazarlar (8)
Hasan Kadı
Balıkesir Üniversitesi, Türkiye
Ahmet İnanır
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Habiboğlu Abdülkadir
Köksal Ceyhan
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fatih Koç
Akdeniz Üniversitesi, Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Orhan Önalan
Karabük Üniversitesi, Türkiye
Şule Arslan
Acıbadem Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Modern Rheumatology
Dergi ISSN 1439-7595 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2012
Cilt No 22
Sayı 2
Sayfalar 238 / 242
DOI Numarası 10.1007/s10165-011-0493-9
Özet
Myocardial fibrosis causes the fragmentation of QRS complexes (fQRS) on ECGs. We hypothesized that the frequency of fQRS could be more common in patients with rheumatoid arthritis (RA) than in control subjects. A total of 56 patients with RA were compared with 35 age-and gender-matched fibromyalgia subjects for fQRS. The fQRS was defined as the presence of an additional R wave, or notching of the R or S wave, or the presence of fragmentation in 2 contiguous leads corresponding to the territory of a major coronary artery. Patients with bundle block on ECG and cardiovascular disease were excluded. Twenty-one patients (37.5%) in the RA group had fQRS, while two patients in the control group (5.7%) had fQRS (p = 0.001). No differences were found between the groups in terms of age, gender, or drug use. Duration of disease - years (interquartile range [IQR]) - was 10 (8) in the fQRS (+) group, while it was 5 (2) in the fQRS (-) group (p<0.001). Multivariate logistic regression analysis revealed that duration of disease was associated with the presence of fQRS (B = 1.5, odds ratio = 4.5, p = 0.004, 95% confidence interval = 1.6-12.7). We found that fQRS on ECG was more common in patients with RA without cardiovascular disease than in age- and gender-matched control subjects. © Japan College of Rheumatology 2011.
Anahtar Kelimeler
ECG | Fragmented QRS | Myocardial fibrosis | Rheumatoid arthritis