The effects of rilmenidine on cardiac autonomic function in healthy volunteers
Yazarlar (5)
Prof. Dr. Ersel Onrat Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Dayimi Kaya Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Kadir Kerpeten Kütahya Evliya Celebi State Hospital, Türkiye
Celal Kilit Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Prof. Dr. Ataç ÇELİK Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Revista Espanola De Cardiologia (Q4) | ||
| Dergi ISSN | 0300-8932 | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2004 |
| Cilt / Sayı / Sayfa | 57 / 8 / 745–750 | DOI | 10.1016/s0300-8932(04)77185-7 |
| Makale Linki | https://linkinghub.elsevier.com/retrieve/pii/S0300893204771857 | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| INTRODUCTION AND OBJECTIVES Rilmenidine is an antihypertensive drug whose antihypertensive effect occurs via a sympatholytic action on the central nervous system. However, the effects of rilmenidine on autonomic cardiovascular function are not clear. The aim of this study was to evaluate the acute effect of rilmenidine on autonomic cardiac function by measuring heart rate variability. SUBJECTS AND METHOD A total of 20 healthy men (mean age, 26±3 years) were included in the study; 1 mg of rilmenidine or placebo was given to participants on different days in a double-blind crossover randomized study protocol. After drug administration, time domain and frequency domain parameters of heart rate variability were determined before and after 2 h with the patient in supine decubitus and during the handgrip exercise with 5-min electrocardiographic recordings. RESULTS Rilmenidine caused an increase in … |
| Anahtar Kelimeler |
| Heart rate variability | Rilmenidine | Sympathovagal balance |
Science Direct
The effects of rilmenidine on cardiac autonomic function in healthy volunteers
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 5 |
| Google Scholar | 7 |