Peripheral vascular endothelial function in essential hyperhidrosis
Yazarlar (11)
Ali Metin Esen
Kosuyolu Heart Education And Research Hospital, Türkiye
Kosuyolu Heart Education And Research Hospital, Türkiye
Prof. Dr. Irfan Barutcu Kosuyolu Heart Education And Research Hospital, Türkiye
Arş. Gör. Semsettin Karaca Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Dayimi Kaya Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Mustafa Kulac
Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Prof. Dr. Ozlem Esen Istanbul Memorial Hospital, Türkiye
Osman Karakaya
Kosuyolu Heart Education And Research Hospital, Türkiye
Kosuyolu Heart Education And Research Hospital, Türkiye
Mehmet Melek
Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Prof. Dr. Ersel Onrat Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Prof. Dr. Ataç ÇELİK Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
Celal Kilit Afyon Kocatepe Üniversitesi Tıp Fakültesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Circulation Journal (Q4) | ||
| Dergi ISSN | 1346-9843 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2005 |
| Cilt / Sayı / Sayfa | 69 / 6 / 707–710 | DOI | 10.1253/circj.69.707 |
| Makale Linki | https://www.jstage.jst.go.jp/article/circj/69/6/69_6_707/_pdf | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| Background Essential hyperhidrosis, a disorder of the eccrine sweat glands, is associated with sympathetic overactivity and the aim of the present study was to determine endothelium-dependent vasodilator function in patients with this condition. Methods and Results Using high-resolution ultrasound, the diameter of the brachial artery at rest and during reactive hyperemia (flow-mediated dilatation,% FMD endothelial-dependent stimulus to vasodilatation), as well as after sublingual administration of nitroglycerin (% NTG endothelium-independent vasodilatation) was measured in 18 subjects (mean age 27±5 years) with essential hyperhidrosis and 24 healthy control subjects (mean age 29±5 years). Baseline brachial artery diameter and FMD were comparable in both groups (BAD: 4.1±0.7 mm vs 4.3±0.5 mm (control), p= 0.8; FMD: 5.6±1.9% vs 6.7±2.2%, p= 0.1). The time-averaged flow velocity during peak reactive hyperemia was similar in the 2 groups (75±11 cm/s vs 72±10 cm/s, p= 0.5), nor did NTG-induced dilatation in the patients with essential hyperhidrosis differ significantly from that in healthy control subjects (12.8±2.7% vs 14.0±3.6%, p= 0.3). Conclusion These findings suggest that endothelium-dependent dilatation of large conduit arteries is preserved in essential hyperhidrosis and it seems to be a localized disorder of the eccrine sweat glands rather than a generalized disorder involving vascular endothelium.(Circ J 2005; 69: 707-710) |
| Anahtar Kelimeler |
| Cardiac autonomic regulation | Endothelial function | Essential hyperhidrosis |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 3 |
| Scopus | 5 |
| Google Scholar | 13 |