Role of Renin Angiotensin converting Enzyme Level and ACE Gene Polymorphism in Patients with Nonalcoholic Fatty Liver Disease
Yazarlar (7)
Fırat Üniversitesi, Türkiye
Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Prof. Dr. Abdurahman ŞAHİN
Fırat Üniversitesi, Türkiye
Fırat Üniversitesi, Türkiye
Fırat Üniversitesi, Türkiye
Fırat Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
| Dergi Adı | Euroasian Journal of Hepato-Gastroenterology |
| Dergi Tarandığı Indeksler | IndexCopernicus |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2016 |
| Cilt No | 6 |
| Sayı | 2 |
| Sayfalar | 137 / 142 |
| Özet |
| Materials and methodsLiver function tests, body mass index, waist circumference, lipid parameters, fasting blood glucose (FBG), hemoglobin A1c (HbA1c), homeostasis model assessment-IR (HOMA-IR), ACE, and ACE gene polymorphism were evaluated in the NAFLD group and control group. The study group was evaluated by dividing the group into four subgroups by ACE gene polymorphism (D/D homozygous, I/I homozygous, D/I heterozygous, I/D heterozygous). Liver biopsies were evaluated according to Brunt Classification.ResultsA total of 31 patients who were diagnosed with NAFLD and 40 healthy individuals were included in the study. The ACE level was found to be 11.69±1.99 in the NAFLD group and 11.52±1.72 in the control group (p= 0.70). There was a negative correlation between ACE levels and HOMA-IR levels (p= 0.008, r=− 0.512). Biochemical parameters were not different among ACE gene … |
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