Evaluation of the association between sexual dysfunction and demyelinating plaque location and number in female multiple sclerosis patients     
Yazarlar (7)
Volkan Solmaz
Türkiye
Hatice Köse Özlece
Türkiye
Aydın Him
Ayfer Güneş
Christian Cordano
Prof. Dr. Dürdane AKSOY Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Yahya Çelik
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı NEUROLOGICAL RESEARCH
Dergi ISSN 0161-6412 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2018
Cilt No 40
Sayı 8
Sayfalar 683 / 688
DOI Numarası 10.1080/01616412.2018.1462752
Makale Linki https://www.tandfonline.com/doi/full/10.1080/01616412.2018.1462752
Özet
Purpose To investigate the frequency of sexual dysfunction (SD) in female multiple sclerosis (MS) patients and to explore its association with the location and number of demyelinating lesions. Material and Methods We evaluated 42 female patients and 41 healthy subjects. All patients underwent neurological examination and 1.5 T brain and full spinal MRI. All subjects completed the female sexual function index (FSFI), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Short-Form 36 Quality of Life Scale (SF-36). All participants were also evaluated for serum thyroid stimulating hormone (TSH), T4, estradiol, and total testosterone. Results No statistically significant differences between the MS and control groups were found for age, body mass index (BMI), serum TSH, T4, E2, and total testosterone level. MS patients had a statistically significantly lower FSFI and SF-36 scores and higher BDI and BAI scores compared with healthy subjects. The location and number of demyelinating lesions were not associated with SD. Conclusion In our cohort, this difference in SD appears unrelated to the location and number of demyelinating lesions. These findings highlight the importance of the assessment and treatment of psychiatric comorbidities, such as depression and anxiety, in MS patients reporting SD.
Anahtar Kelimeler
Multiple sclerosis | sexual dysfunction | demyelinating lesions | magnetic resonance