ACTN3 R577X variant: could it be a determinant of sports performance in elite athletes in a Turkish population?
Yazarlar (4)
Prof. Dr. Abdullah CANİKLİ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ayşe Feyda Nursal Hitit Üniversitesi, Türkiye
Şaban Ünver Türkiye
Prof. Dr. Serbülent Yiğit Ondokuz Mayıs Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Genetics (Q4) | ||
| Dergi ISSN | 0022-1333 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 03-2022 |
| Cilt / Sayı / Sayfa | 101 / 22 / 1–6 | DOI | 10.1007/s12041-022-01362-1 |
| Makale Linki | http://dx.doi.org/10.1007/s12041-022-01362-1 | ||
| UAK Araştırma Alanları |
Antrenman
Egzersiz ve Spor Fizyolojisi
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| Özet |
| ACTN3 gene, which encodes α-actinin-3 and actin-binding protein, has been found to be associated with strong athletic performance, especially among track and field athletes. Therefore, in this study, our aim was to compare the allelic and genotype frequencies of the ACTN3 R577X variant among elite athletes specialized in different branches, and nonathletic controls in Turkey. In the present study, 316 subjects, including 168 athletes and 148 sedentary controls were genotyped for the ACTN3 R577X variant. Genotyping was conducted by polymerase chain reaction (PCR) method. Additionally, we evaluated the groups by dividing them as females and males. There were 48 females and 120 males in the athletes group, and 43 females and 105 males in the control group. Genetic associations were evaluated by chi-squire test or Fisher’s exact test. There was a significant difference between the athletes and … |
| Anahtar Kelimeler |
| ACTN3 gene | elite athletes | Turkish population | variant |
| Atıf Sayıları | |
| Web of Science | 4 |
| Google Scholar | 7 |