Investigation of antioxidant and antimicrobial activities of walnut (Juglans regia L.) kernel septum
Yazarlar (2)
Dr. Öğr. Üyesi Elif Azize ÖZŞAHİN DELİBAŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Esin Kıray Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | The European Research Journal | ||
| Dergi ISSN | 2149-3189 | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2023 |
| Cilt / Sayı / Sayfa | 9 / 1 / 87–96 | DOI | 10.18621/eurj.1056629 |
| Makale Linki | https://dergipark.org.tr/en/download/article-file/2187404 | ||
| Özet |
| Objectives Walnut (Juglans regia L.) kernel septum (or septa) (WKS), a traditional nutraceutical material in China, has not been explored in detail. In this study, antimicrobial activity, total phenolic content (TPC) and antioxidant-oxidant status of WKS was investigated in case it may be clinically important in the management of various complications. Methods The WKS was extracted with ethanol in a Soxhlet device. TPC of WKS was analysed by using Folin-Ciocalteu’s method. Antioxidant activity was obtained by using Rel Assay Diagnostics kits. The antimicrobial activity of WKS was evaluated against two Gram-positive (Staphylococcus aureus, Bacillus subtilis), one Gram-negative bacteria (Escherichia coli) and one fungus (Candida albicans) strains using the agar diffusion method.Results The TPC of WKS was found to be 119.42 ± 2.39 mg GAE/gDW. It was determined that total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) values were 7.542 ± 0.389 mmol/L, 3.718 ± 0.287 µmol/L and 0.049 ± 0.001, respectively. WKS selectively inhibited the growth of Gram-positive bacteria and fungus, while S. aureus was the most susceptible one with 16 mm of inhibition zone. Gram-negative bacteria was resistant to the extract.Conclusions As far as we know, this paper is the first work that demonstrates the antioxidant-oxidant status of WKS by using the method described above, and moreover there are no scientific reports which have examined WKS in such a multidisciplinary experimental design. This study strongly supports the reported traditional use of WKS. Results indicated that WKS can be used as a pharmacological … |
| Anahtar Kelimeler |
| Juglans regia L | walnut kernel septum | antioxidant | total phenolic content | antimicrobial activity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 13 |