Molecular Analysis of Genetic Variation in AngiotensinI Converting Enzyme Gene in Turkish Athletes
Yazarlar (5)
Ahmet İnanır Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Abdullah CANİKLİ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ercan Tural Ondokuz Mayıs Üniversitesi, Türkiye
Akın Tekcan Ahi Evran Üniversitesi, Türkiye
Şengül Tural Ondokuz Mayıs Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı INTERNATIONAL JOURNAL OF HUMAN GENETICS (Q4)
Dergi ISSN 0972-3757 Dergi Bilgileri (2014)
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 06-2014
Cilt / Sayı / Sayfa 14 / 2 / 101–105 DOI 10.1080/09723757.2014.11886232
Makale Linki https://www.tandfonline.com/doi/full/10.1080/09723757.2014.11886232
UAK Araştırma Alanları
Antrenman Bilimi
Özet
Genetic factors play an important role in physical performance. The angiotensin converting enzyme (ACE) gene polymorphism is the most studied genetic marker in the field of human performance. The aim of this study was to determine the impact of ACE (I/D) polymorphism on athletic ability in Turkish athletes. Genomic DNA obtained from 237 persons (120 athletes and 117 sedentary controls) was used in the study. ACE gene I/D polymorphism genotypes were determined by using polymerase chain reaction with the specific primers. Results revealed that the ACE genotype distribution was significantly different between athletes (II 16.7%, ID 43.3% and DD 40%) and sedentary groups (II 7.7%, ID 38.5% and DD 53.8%; P= 0.036). The D allele frequency was obserwed as 38.3% and I allele was as 61.7% in the athlets group, it was 26.92% and 73.08% respectively in the control group. As a result of our study …
Anahtar Kelimeler
ACE Gene | Polymorphism | Athletic Ability | Genetic Variation | Polymerase Chain Reaction
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 2
Google Scholar 6
Molecular Analysis of Genetic Variation in AngiotensinI Converting Enzyme Gene in Turkish Athletes