The Endothelial Nitric Oxide Synthase Gene Variant rs2070744 in Turkish Elite Athletes
Yazarlar (5)
Prof. Dr. Abdullah CANİKLİ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ayşe Feyda Nursal Giresun Üniversitesi, Türkiye
Akın Tekcan Ahi Evran Üniversitesi, Türkiye
Prof. Dr. Funda DEMİRTÜRK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Serbülent Yiğit Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
|
||
| Dergi Adı | The Annals of Eurasian Medicine | ||
| Dergi ISSN | 2147-7094 | ||
| Dergi Tarandığı Indeksler | Index Copernicus, Citefactor, Pleksus Medline, Türkiye Atıf Dizini | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2016 |
| Cilt / Sayı / Sayfa | 4 / 2 / 31–34 | DOI | 10.4328/AEMED.85 |
| Makale Linki | https://archive.org/download/the-endothelial-nitric-oxide-synthase-gene-variant-rs2070744-in-turkish-elite-athletes/10.4328.ECAM.85.pdf | ||
| UAK Araştırma Alanları |
Antrenman Bilimi
|
||
| Özet |
| Aim: Genetic variations have been associated with physical performance. The Endothelial Nitric Oxide Synthase (eNOS) gene variants have been widely studied in this context. The aim of the present study is to compare the T-786C variant of the eNOS gene in Turkish elite athletes and control groups. Methods: DNA samples were obtained from 52 elite athletes (45 male, 7 female) and 60 controlsubjects (49 male, 11 female). The T-786C variant of the eNOS gene was genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method.Results: TT, TC, CC genotypes of the T-786C variant of eNOS gene were observed in 40.0%, 48.3%, and 11.6% ofcontrol subjects and in 55.7%, 30.7% and 13.4% of elite athletes, respectively. There was not any statistically significant difference in genotype and allele frequencies of T-786C of the eNOS between the elite athlete and the control groups (p> 0.05).Conclusion: The present study demonstrated that the T-786C variant of the eNOS gene is not associated withstudy population but larger sample analyses are needed in different groups of elite athletes in order to substantiate these findings. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 2 |