Ultrasound-Assisted Extraction of Free and Bound Phenolics from Hawthorn (Crataegus azarolus) Leaves and their Antioxidant and Antidiabetic Activities
Yazarlar (4)
Esra Esin
Semra Topuz Turker
Prof. Dr. Mustafa BAYRAM Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Cemal KAYA Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | PLANT FOODS FOR HUMAN NUTRITION (Q2) | ||
| Dergi ISSN | 0921-9668 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 05-2026 |
| Cilt / Sayı / Sayfa | 81 / 2 / – | DOI | 10.1007/s11130-026-01505-0 |
| Makale Linki | https://doi.org/10.1007/s11130-026-01505-0 | ||
| UAK Araştırma Alanları |
Gıda Teknolojileri
Fermantasyon Teknolojileri
|
||
| Özet |
| Hawthorn (Crataegus azarolus) leaves are an underutilized plant resource with potential as a source of bioactive phenolic compounds. This study investigated the ultrasound-assisted extraction (UAE) of free and bound phenolics from hawthorn leaves and evaluated their functional properties. The extraction parameters were optimized using response surface methodology (RSM) to maximize the total phenolic content (TPC) and total flavonoid content (TFC). Under optimal conditions, the free phenolic content reached 78.61 mg GAE g− 1 dry weight (DW), whereas the bound phenolic content reached 13.56 mg GAE g− 1 DW, accounting for approximately 15% of the total phenolic content. The free phenolic fraction exhibited higher antioxidant activity than the bound fraction in the ABTS, DPPH, and FRAP assays. Both fractions inhibited α-amylase and α-glucosidase, demonstrating their in vitro enzyme inhibitory … |
| Anahtar Kelimeler |
| Free and bound phenolic compounds | Ultrasound-assisted extraction | Response surface methodology | Antioxidant activity | Antidiabetic potential |
| Atıf Sayıları | |
| Web of Science | 2 |
| Google Scholar | 3 |