Antioxidant and cytotoxic activities of silver nanoparticles synthesized using Tilia cordata flowers extract       
Yazarlar (2)
Doç. Dr. Kadriye Özlem SAYGI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ercan ÇAÇAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Materials Today Communications
Dergi ISSN 2352-4928 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 06-2021
Cilt No 27
Sayı 1
DOI Numarası 10.1016/j.mtcomm.2021.102316
Makale Linki http://dx.doi.org/10.1016/j.mtcomm.2021.102316
Özet
In the past several years, the interest in synthesizing nanoparticles from plant extract has been increasing due to easy, low cost and being clean. In this study, Tilia cordata flower (Tcf) extract was used as bioreduction of silver nitrate to form silver nanoparticles (AgNPs). Visual formation of nanoparticles was confirmed by a color change from light yellow to brown. The structural properties and morphology of Tcf-AgNPs were confirmed by Ultraviolet-visible (UV–vis), Fourier transform infrared (FT-IR), Scanning electron microscope with Energy dispersive X-ray (SEM/EDX), High resolution transmission electron microscope (HR-TEM) and X-ray diffraction (XRD) spectroscopic techniques. The antioxidant capacity of AgNPs was investigated in vitro by ferric reducing antioxidant power (FRAP), 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazolibe-6-sulphonic acid) ABTS assays. DPPH activities were found as good as standard, BHT with the values of 9.40 (IC50, μg/mL) and 9.67 (IC50, μg/mL) respectively. The anti-tumor effect of Tcf-AgNPs was determined by MTT assays and the results indicate that Tcf-AgNPs have cytotoxic activities in a cell line and dose-dependent manner.
Anahtar Kelimeler
Anti-tumor | Antioxidant | Green synthesis | Natural plant | Silver nanoparticles | Tilia cordata