Sclerostin as a biomarker of physical exercise in osteoporosis: A narrative review
Yazarlar (8)
Akademia Wychowania Fizycznego We Wroclawiu, Polonya
Akademia Wychowania Fizycznego We Wroclawiu, Polonya
St Hedwig Of Silesia Hospital, Polonya
Akademia Wychowania Fizycznego We Wroclawiu, Polonya
Prof. Dr. Erşan ARSLAN
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Instituto Politécnico De Viana Do Castelo, Portekiz
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Akademia Wychowania Fizycznego We Wroclawiu, Polonya
| Makale Türü |
Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği,
araştırma notu, bilirkişi raporu ve benzeri)
|
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Frontiers in Endocrinology |
| Dergi ISSN | 1664-2392 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2022 |
| Cilt No | 13 |
| Sayı | 1 |
| DOI Numarası | 10.3389/fendo.2022.954895 |
| Makale Linki | http://dx.doi.org/10.3389/fendo.2022.954895 |
| Özet |
| Osteoporosis, a disease of low bone mass, is characterized by reduced bone mineral density (BMD) through abnormalities in the microarchitecture of bone tissue. It affects both the social and economic areas, therefore it has been considered a lifestyle disease for many years. Bone tissue is a dynamic structure exhibiting sensitivity to various stimuli, including mechanical ones, which are a regulator of tissue sclerostin levels. Sclerostin is a protein involved in bone remodeling, showing an anti-anabolic effect on bone density. Moderate to vigorous physical activity inhibits secretion of this protein and promotes increased bone mineral density. Appropriate exercise has been shown to have an osteogenic effect. The effectiveness of osteogenic training depends on the type, intensity, regularity and frequency of exercise and the number of body parts involved. The greatest osteogenic activity is demonstrated by exercises affecting bone with high ground reaction forces (GRF) and high forces exerted by contracting muscles (JFR). The purpose of this study was to review the literature for the effects of various forms of exercise on sclerostin secretion. |
| Anahtar Kelimeler |
| bone mineral density | exercise | osteoporosis | physical activity | physical training | sclerostin |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 20 |
| SCOPUS | 21 |
| Google Scholar | 26 |