Fusogenic lipid nanocarriers: Nature-inspired design for advanced drug delivery systems
Yazarlar (4)
Gennaro Balenzano Universität Innsbruck, Avusturya
Dr. Öğr. Üyesi Numan ECZACIOĞLU Universität Innsbruck, Avusturya
Nunzio Denora Università Degli Studi Di Bari Aldo Moro, İtalya
Andreas Bernkop-Schnurch Universität Innsbruck, Avusturya
| Makale Türü |
Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği,
araştırma notu, bilirkişi raporu ve benzeri)
(SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not,
editöre mektup, tartışma, vaka takdimi ve özet türünden makale)
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| Dergi Adı | Advances in Colloid and Interface Science (Q1) | ||
| Dergi ISSN | 0001-8686 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 09-2025 |
| Cilt / Sayı / Sayfa | 346 / 1 / 103667–0 | DOI | 10.1016/j.cis.2025.103667 |
| Makale Linki | https://doi.org/10.1016/j.cis.2025.103667 | ||
| UAK Araştırma Alanları |
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| Özet |
| Lipid nanocarriers are a useful tool for intracellular delivery of drugs that are otherwise unable to enter their target cells. Most of these nanocarriers are designed for an endocytotic uptake, although this route of intracellular drug delivery has a number of shortcomings. A promising alternative is fusogenic lipid nanocarriers, since by this uptake mechanism lysosomal degradation problems being associated with endocytosis can be excluded and drug release into the target cell can be synchronized with the fusion process. Various mechanisms being responsible for biological fusion events, including fertilization, exocytosis, viral infection and plasma membrane repair can be copied and transferred to nanocarriers enabling them to fuse with target cells. In particular, curvature, fluidity and surface charge of nanocarriers are key parameters for fusogenic properties. Furthermore, lipid nanocarriers can be decorated with ... |
| Anahtar Kelimeler |
| Lipid nanocarriers | Lipid nanoparticles | Fusion | Fusogenic liposomes | Endocytosis | Membrane fluidity | Cellular uptake |
Science Direct
Fusogenic lipid nanocarriers: Nature-inspired design for advanced drug delivery systems
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 22 |
| Scopus | 23 |
| Google Scholar | 24 |
| PubMed | 5 |