A dual-responsive fluorescent sensor for selective detection of cyanide ions and histamine via distinct mechanisms in food samples
Yazarlar (4)
Dr. Öğr. Üyesi Fuat Gökbel Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Dr. Öğr. Üyesi Numan ECZACIOĞLU Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Doç. Dr. Numan Emre Gümüş Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Doç. Dr. Ziya Aydın Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Microchemical Journal (Q1)
Dergi ISSN 0026-265X Dergi Bilgileri (2025)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 08-2025
Cilt / Sayı / Sayfa 215 / 1 / 114553–0 DOI 10.1016/j.microc.2025.114553
Makale Linki https://doi.org/10.1016/j.microc.2025.114553
UAK Araştırma Alanları
Analitik Kimya Spektroskopi
Özet
Ensuring food safety requires rapid, sensitive detection of toxic contaminants like cyanide ions and spoilage markers like biogenic amines (BAs). Here, we present FZ-3 (combining 2,3,3-trimethyl-1-propyl-3H-indole-1-ium iodide with a pyridine moiety), a novel dual-sensitive fluorescent sensor that selectively detects cyanide ions (CN−) and histamine (His) through distinct reaction mechanisms. FZ-3 combines an indolium moiety for cyanide ions recognition via nucleophilic addition and, with a chloropyridine unit for His sensing via substitution. With minimal interference from other ions/biogenic amines, the sensor exhibits a turn-on response for CN− ions at 414 nm, while for His it enhances emission with a turn-on response at 463 nm. It demonstrates excellent sensitivity with detection limits of 1.08 μM for CN− and 2.80 μM for His, surpassing many existing single-analyte detection systems. FZ-3's efficacy was ...
Anahtar Kelimeler
Chemosensor