Comprehensive and sensitive validation of the method and determination of measurement uncertainty for simultaneous specification of aflatoxin B1, B2, G1 and G2 in nuts
Yazarlar (3)
Doç. Dr. Hacer Sibel Karapınar Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Dr. Öğr. Üyesi Numan ECZACIOĞLU Karamanoğlu Mehmetbey Üniversitesi, Türkiye
Arş. Gör. Faruk Doğan Karamanoğlu Mehmetbey Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Measurement Food | ||
| Dergi ISSN | 2772-2759 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2024 |
| Cilt / Sayı / Sayfa | 13 / 1 / 100124–0 | DOI | 10.1016/j.meafoo.2023.100124 |
| Makale Linki | http://dx.doi.org/10.1016/j.meafoo.2023.100124 | ||
| UAK Araştırma Alanları |
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| Özet |
| In this study, a comprehensive and sensitive validation study of the legally used method was conducted to simultaneously determine the levels of aflatoxin B1, B2, G1, and G2 in nuts. The applied method has been extensively evaluated in terms of in-laboratory detection limit and quantification limit, linearity, selectivity, precision, recovery, accuracy, adequacy, and measurement uncertainty. Levels of aflatoxins were examined by a validated immunoaffinity column-high performance liquid chromatography-post column derivatization-fluorescence detection (IAC-HPLC-PCA-FLD) analytical method. Detection limits (LOD) for aflatoxin G2, G1, B2, and B1 were found to be 0.05 μg/kg, 0.13 μg/kg, 0.06 μg/kg, and 0.15 μg/kg, respectively. The regression coefficient (R2) was greater than 0.999 according to constructed calibration curves for all aflatoxin components. Thus, the curves exhibited satisfactory linearity within the ... |
| Anahtar Kelimeler |
| Aflatoxin | High pressure liquid chromatography | Nuts | Proficiency test performance | Uncertain measurement | Validation |
Science Direct
Comprehensive and sensitive validation of the method and determination of measurement uncertainty for simultaneous specification of aflatoxin B1, B2, G1 and G2 in nuts
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Yöksis | 1 |
| Web of Science | 8 |
| Scopus | 7 |
| Google Scholar | 8 |