Clinical Outcomes of Kaposi's Sarcoma Treated with Systemic Chemotherapy
Yazarlar (4)
Abdilkerim Oyman Sağlık Bilimleri Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mustafa BAŞAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Melike Özçelik Sağlık Bilimleri Üniversitesi, Türkiye
Mahmut Emre Yıldırım Sağlık Bilimleri Üniversitesi, Türkiye
Makale Türü Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Eurasian Journal of Medical Investigation
Dergi ISSN 2602-3164
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce Basım Tarihi 01-2021
Cilt / Sayı / Sayfa 5 / 1 / 12–15 DOI 10.14744/ejmi.2020.96330
Makale Linki http://dx.doi.org/10.14744/ejmi.2020.96330
UAK Araştırma Alanları
Sağlık Bilimleri
Özet
Objectives: We aimed to examine the clinical and epidemiological features of the patients diagnosed with Kaposi’ssarcoma, who were treated with systemic chemotherapy.Methods: Patients with age of 18 years or older and histopathologically confirmed Kaposi sarcoma, were included inthe study. Demographic data, tumor histology and characteristics, Kaposi’s sarcoma subtype and treatment modalitieswere retrospectively evaluated.Results: A total of 20 patients were included in the study. Fourteen patients (70%) were found to be related with HHV8. Five patients (25%) were HIV-positive. The lesions were located in the lower extremities in 19 patients (95%), upperextremities in 11 patients (55%), head and neck in 11 patients (55%) and trunk in 6 patients (30%). All 20 patients unresponsive to the local treatments including two patients with visceral metastases received chemotherapy. Completeremission was achieved in seven patients (35%), partial response was achieved in seven patients (35%) and stableresponse was achieved in four patients (20%) with the systemic chemotherapy.Conclusion: The success rate is high with the practice of local treatments. The aggressive state of the disease which isineligible for local treatment can be controlled by systemic chemotherapy.
Anahtar Kelimeler
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Yöksis 1
Clinical Outcomes of Kaposi's Sarcoma Treated with Systemic Chemotherapy