Free and liposome form of gallic acid improves calvarial bone wound healing in Wistar rats
Yazarlar (7)
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Hatice BALCI YÜCE
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Özkan KARATAŞ
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Mehmet Murat TAŞKAN
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fikret GEVREK
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Sefa ÇOLAK
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Asian Pacific Journal of Tropical Biomedicine |
| Dergi ISSN | 2221-1691 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2020 |
| Cilt No | 10 |
| Sayı | 4 |
| Sayfalar | 156 / 163 |
| DOI Numarası | 10.4103/2221-1691.280297 |
| Makale Linki | http://www.apjtb.org/text.asp?2020/10/4/156/280297 |
| Özet |
| Objective:To evaluate the effect of free and liposome form of gallic acid on bone regeneration in critical defects in Wistar rats.Methods:Thirty-two female Wistar rats were divided into four study groups: group 1, negative control; group 2, positive control; group 3, gallic acid powder; group 4, gallic acid liposome. A critical-sized defect was created in all rats. Groups 2 to 4 had xenograft, autograft and membrane placement while negative control rats did not receive any treatment. The defect area was sutured and rats were kept alive for 30 d. At the end of the study, a bone specimen including the defect area was removed from calvaría. All specimens were evaluated under the stereomicroscope, then underwent histological analysis. Inflammatory cell counts, osteoblast, osteoclast counts, receptor activator of nuclear factor κ-B (RANKL), osteoprotegerin (OPG), runt-related transcription factor 2 (Runx2), bone morphogenetic … |
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BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 18 |
| Google Scholar | 24 |