The Importance and Side Effects of Radiotherapy For Diffuse Pigmented Villonodular Synovitis; Case Reports and Literature Review   
Yazarlar (1)
Doç. Dr. Gülhan GÜLER AVCI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Açık Erişim Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı ACTA ONCOLOGICA TURCICA
Dergi ISSN 0304-596X
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce
Basım Tarihi 01-2020
Cilt No 53
Sayı 1
Sayfalar 162 / 165
DOI Numarası 10.5505/aot.2020.42744
Makale Linki http://dx.doi.org/10.5505/aot.2020.42744
Özet
Pigmented villonodular synovitis (PVNS) is a rare, well-behaved disease involving the synovial membrane and joints. Diffuse PVNS has high recurrence rate with surgery alone. We aimed to present the results and side effects of radiotherapy (RT) in two cases with PVNS in the light of literature. Two female patients were admitted to our hospital with pain and swelling on their right knees. Magnetic resonance imaging (MRI) showed a solid mass in the kneejoints. Patients who were thought to have PVNS radiologically, underwent total synovectomy. Patients with diffuse PVNS received postoperative 32 and 36 Gy RT on account of uncertain surgical margin status. No acute side effects related to radiotherapy were observed in the both cases. In one case, one year after radiotherapy, the articular effusion and peripatellar pain evolved as a late complication. There were no local recurrence at 31 and 32 months follow-up. As a result, radiotherapy is a safe and effective treatment option for preventing recurrence of diffuse PVNS and provides protection of extremities in very advanced cases. However, more studies with long-term follow-up are needed.
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