Clinical Utility of Red Blood Cell Distribution Width Parameter in Patients with Hemodynamically Stable Acute Pulmonary Embolism       
Yazarlar (2)
Prof. Dr. Ahmet Cemal PAZARLI T.C. Sağlık Bakanlığı, Türkiye
Lütfü Bekar
Hitit Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü ESCI dergilerinde yayınlanan tam makale
Dergi Adı Solunum
Dergi ISSN 1302-4922
Dergi Tarandığı Indeksler Emerging Sources Citation Index, EBSCO, CINAHL, ProQuest
Makale Dili İngilizce
Basım Tarihi 05-2014
Cilt No 16
Sayı 1
Sayfalar 27 / 30
DOI Numarası 10.5152/ejp.2014.64872
Makale Linki http://dx.doi.org/10.5152/ejp.2014.64872
Özet
Objective: Patients with acute pulmonary embolism (PE) presenting with persistent hypotension or shock are considered to be high-risk, while hemodynamically stable patients with acute PE are classified as low- or moderate-risk, depending on their right ventricular dysfunction and/or levels of biomarkers indicating myocardial injury. In this study, we assessed the clinical benefits of knowing the red cell distribution width (RDW) parameter in patients with hemodynamically stable acute PE. Methods: All patients diagnosed with acute PE in our hospital between 2008 and 2010 were retrospectively included in the study. Patients with hypotension, a history of malignancy, heart failure, and/or anemia were excluded. Patients with normotensive acute PE were divided into either a low- or moderate-risk group. This classification was made according to echocardiographic right ventricular dysfunction, positive troponin T, and the level of NT-proBNP. Red cell distribution width values of low and moderate acute PE risk groups were compared.Results: Thirty-two patients were assessed as moderate-risk and 34 patients were low-risk PE. Red cell distribution width values of the moderate-risk group were significantly higher than those of the low-risk group (14.77±0.54 vs. 14.09±0.43; p=0.036, respectively).Conclusion: Analysis of RDW values can help to determine the low and moderate risk levels of hemodynamically stable patients with acute PE
Anahtar Kelimeler
Acute pulmonary embolism | red blood cell distribution width | risk classification