Obstructive sleep apnea, renin-angiotensin system, and COVID-19: possible interactions
    
Yazarlar (3)
Timur Ekiz
Türkmenbaşı Medical Center, Türkiye
Prof. Dr. Handan İNÖNÜ KÖSEOĞLU Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ahmet Cemal PAZARLI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Açık Erişim Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale)
Dergi Adı Journal of Clinical Sleep Medicine (Q1)
Dergi ISSN 1550-9389 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2020
Kabul Tarihi 02-04-2026 Yayınlanma Tarihi 15-08-2020
Cilt / Sayı / Sayfa 16 / 8 / 1403–1404 DOI 10.5664/jcsm.8576
Makale Linki https://jcsm.aasm.org/doi/pdf/10.5664/jcsm.8576
Özet
Because hypertension (HT) is a primary risk factor for severe disease and mortality in the ongoing coronavirus disease 2019 (COVID-19) pandemic, the renin-angiotensin system (RAS) is of much greater concern as the main underlying physiopathology of HT. 1 However, obstructive sleep apnea (OSA), repetitive episodes of complete/partial cessation of airflow (breathing) during sleep, is associated with dysregulation of the RAS, and HT is a significant comorbidity among patients with OSA. 2 Accordingly, in this report, we draw attention to the possible interactions among OSA, RAS, and COVID-19.Describing the RAS is helpful to better explain these interactions. The RAS has 2 primary pathways: classical and nonclassical. In the former, angiotensinogen is converted to angiotensin I by renin that is secreted from the kidneys. Then angiotensin I is converted to angiotensin II by the angiotensinconverting enzyme …
Anahtar Kelimeler
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 34
Scopus 4
Web of Science 14
Obstructive sleep apnea, renin-angiotensin system, and COVID-19: possible interactions

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