GC–MS analysis and anti–microbial activity of Prunella vulgaris L. extracts       
Yazarlar (4)
Doç. Dr. Oğuz ÖZBEK Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Burak Sağlam
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Necibe Canan USTA Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Yakup BUDAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Journal of the Indian Chemical Society
Dergi ISSN 0019-4522 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili Türkçe
Basım Tarihi 06-2022
Cilt No 99
Sayı 6
Sayfalar 100460 / 0
DOI Numarası 10.1016/j.jics.2022.100460
Makale Linki http://dx.doi.org/10.1016/j.jics.2022.100460
Özet
In this study, the chemical composition of the methanol, hexane and ethyl acetate extracts of Prunella vulgaris L. were investigated by gas chromatography–mass spectrometry (GC–MS) method. 2-hydroxy-5-methylbenzaldehyde (15.70%), linolenic acid (45.50%) and icosane (16.24%) were found to be the most abundant in methanol, hexane and ethyl acetate extracts, respectively. Following the determination of chemical components of the Prunella vulgaris L. extracts, their anti–microbial activities against certain human pathogenic bacteria were tested and minimal inhibitory concentrations (MIC) were determined. While some extracts of Prunella vulgaris L. show anti–microbial activity well above the standards (penicillin and tetracycline), it was determined that in general all the extracts showed good anti–microbial activity against these pathogenic bacteria.
Anahtar Kelimeler
Anti–microbial activity | GC-MS | Pathogen | Prunella vulgaris L.