Utility of Systematic Coronary Risk Evaluation (SCORE) System to Predict Coronary Artery Disease Severity in Low to Moderate Risk Hypertensive Patients Undergoing Elective Coronary Angiography   
Yazarlar (5)
Mehmet Eyüboğlu
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Metin KARAYAKALI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Kayıhan KARAMAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Arif Arısoy
Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayınlanan tam makale
Dergi Adı Arterial Hypertension
Dergi ISSN 2449-6170 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler Emerging Sources Citation Index
Makale Dili İngilizce
Basım Tarihi 09-2020
Cilt No 24
Sayı 3
Sayfalar 128 / 134
DOI Numarası 10.5603/AH.a2020.0017
Makale Linki https://journals.viamedica.pl/arterial_hypertension/article/view/69835
Özet
Background: Coronary artery disease (CAD) is the leading cause of mortality in hypertensive patients. Systematic Coronary Risk Evaluation (SCORE) is the preferred scoring system to predict future fatal cardiovascular events in hypertensive patients. However, the relationship between SCORE and coronary atherosclerosis is not well described. We aimed to investigate whether SCORE has a relationship with CAD severity in hypertensive patients, even in the absence of high risk features.Material and methods: Four hundred and fifty-two hypertensive patients who underwent elective coronary angiography and defined as low or moderate risk according to SCORE were included into the study. Patients were divided into two groups. Patients with a SCORE< 1% were defined as low risk group, and patients with a SCORE≥ 1% and< 5% were defined as moderate risk group. The groups were compared regarding CAD severity.Results: The frequency of stenotic CAD and multivessel disease, and mean SYNTAX score, were significantly higher in SCORE≥ 1%, and< 5% group compared to patients with SCORE< 1%. Correlation analysis revealed a significant positive moderate correlation between SCORE and SYNTAX score (Pearson’sr: 0.679, p< 0.001). ROC curve analysis demonstrated that a SCORE≥ 3% predicted SYNTAX score> 22 with a sensitivity of 75% and a specificity of 86.5%(AUC: 0.879, p< 0.001). Furthermore, multivariate analysis demonstrated that SCORE was an independent predictor of stenotic CAD (OR: 1.616, p< 0.001), multivessel disease (OR: 1.913, p< 0.001), and SYNTAX score> 22.(OR: 1.817, p< 0.001).Conclusion: Our …
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