The Relationship Between Endothelial Damage and Aortic Augmentation Index
Yazarlar (8)
Ömer Gedikli Karadeniz Teknik Üniversitesi, Türkiye
Abdulkadir Kırış Karadeniz Teknik Üniversitesi, Türkiye
Hülya Yılmaz
Serkan Öztürk Abant İzzet Baysal Üniversitesi, Türkiye
Merih Kutlu Karadeniz Teknik Üniversitesi, Türkiye
İsmet Durmuş Karadeniz Teknik Üniversitesi, Türkiye
Doç. Dr. Kayıhan KARAMAN Gaziosmanpaşa Üniversitesi, Türkiye
Süleyman Caner Karahan Karadeniz Teknik Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Clinical and Experimental Hypertension (Q3) | ||
| Dergi ISSN | 1064-1963 Dergi Bilgileri (2010) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2010 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-02-2010 |
| Cilt / Sayı / Sayfa | 32 / 1 / 29–34 | DOI | 10.3109/10641960902960524 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.3109/10641960902960524 | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| Augmentation index (AIx), a measure of wave reflection, is regulated by a number of factors, including endothelial function and vascular smooth muscle tone. The relationship between local endothelium-derived factors and AIx is well known; however, association between endothelial damage markers and AIx has not been sufficiently studied. This study investigates whether endothelial damage markers—von Willebrand factor (vWF) soluble thrombomodulin (sTM)—are associated with wave reflections. We studied 46 (48.5 ± 10.6, years) never-treated patients with hypertension (HT) and an age-matched control group of 40 (47 ± 8.6, years) normotensive individuals. von Willebrand factor and sTM levels were determined in all subjects. We evaluated the aortic AIx of the study population using applanation tonometry (Sphygmocor, AtCor Medical, Sydney, Australia). The heart rate-corrected augmentation index (AIx@75 … |
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| Yöksis | 2 |
| Google Scholar | 17 |