Prognostic importance of neutrophil / lymphocyte and lymphocyte / crp ratio in cases with malignant bowel obstruction
Yazarlar (6)
Doç. Dr. Emin Daldal Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ahmet Akbaş
Doç. Dr. Mehmet Fatih DAŞIRAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Hasan Dagmura
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Hüseyin Bakır Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. İsmail Okan Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
Dergi Adı medicine sience
Dergi ISSN 2147-0634
Dergi Tarandığı Indeksler index copernicus, DOAJ, Google scholar
Makale Dili Türkçe Basım Tarihi 12-2019
Cilt / Sayı / Sayfa 8 / 4 / 927–930 DOI 10.5455/medscience.2019.08.9114
Makale Linki https://www.bibliomed.org/mnsfulltext/53/53-1574539105.pdf?1614168250
UAK Araştırma Alanları
Genel Cerrahi
Özet
The aim of this study is to present the importance of systemic inflammatory markers in patients with malignant bowel obstruction (MBO) due to intra-abdominal tumor metastasis. Patients who developed MBO due to end-stage intra-abdominal metastatic tumoral disease between October 2010 and September 2018 were retrospectively investigated. Clinical data such as age, sex, histopathological diagnosis of primary tumor and the level of obstruction due to tumor metastasis were recorded. Patients who were still receiving chemotherapy and had no metastatic involvement in the abdomen were excluded from the study. Patients with MBO who developed intra-abdominal metastasis from non-abdominal tumors were included. In the determination of the patients, whether or not the patient had previously operated for primary tumor was not taken into consideration. Neutrophil, lymphocyte ratio (NLR) and lymphocyte CRP ratio (LCR) were determined using laboratory data including the results of neutrophil, lymphocyte, C-reactive protein (CRP) and other basic hematological parameters. The effect of these values on survival as a prognostic factor was compared with statistical methods. There were 74 patients (28 females, 46 males) aged 60.5±12.8 years (27-88) who developed MBO due to tumor metastasis in the abdomen. It was detected that the diagnosis of MBO developed an average of 11±7.5 months after the primary diagnosis. As a result of statistical evaluations, we found a positive correlation between serum LCR and survival (r= 0.433; p= 0.001) and a negative correlation between serum NLR and survival (r=-0.202; p= 0.085). According to the …
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