Synthesis and anti-bacterial activity of novel 1,3-pheylene-bis-N-acetyl- and N-phenylpyrazole derivatives
Yazarlar (4)
Prof. Dr. Meliha Burcu GÜRDERE Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Mustafa CEYLAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Yakup BUDAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | ORGANIC COMMUNICATIONS | ||
| Dergi ISSN | 1307-6175 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | ESCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2017 |
| Cilt / Sayı / Sayfa | 10 / 2 / 90–98 | DOI | 10.25135/acg.oc.12.16.12.453 |
| Makale Linki | http://www.acgpubs.org/OC/2017/Volume2010/Issue201/12-OC-1612-453.pdf | ||
| Özet |
| Pyrazole ring is well known for their wide range of biological activities such as analgesic, antiinflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, psychoanaleptic, monoamine oxidase inhibitor, anti-diabetic and antimicrobial properties. 1-8 Addition, pyrazole derivatives play an important role in the development of pesticides and medicines. Several of pyrazole products are available and widely used as fungicides, antiviral agents, analgesic agents, insecticides and herbicides. 9–11 For thus, pyrazole derivatives have attracted considerable attention in the recent years for their diverse biological activities. 12–17In this paper, the novel 1, 1'-(5, 5'-(1, 3-phenylene) bis (3-aryl-4, 5-dihydro-1H-pyrazole-5, 1-diyl)) diethanone (5a-e) and 1, 3-bis (1-phenyl-3-(aryl)-4, 5-dihydro-1H-pyrazol-5-yl) benzene (6a-e) were synthesized in good yields and evaluated the antibacterial activities of compounds (5a-e) against some human pathogenic bacteria. |
| Anahtar Kelimeler |
| 1,3-Phenylene-bis-N-acetylpyrazoles | 1,3-phenylene-bis-N-phenylpyrazoles | antibacterial activity |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 3 |
| Web of Science | 3 |