Triethylamin mediated addition of 2 aminoethanethiol hydrochloride to chalcones Synthesis of 3 2 aminoethylthio 1 aryl 3 thiophen 2 yl propan 1 ones and 5 7 diaryl 2 3 6 7 tetrahydro 1 4 thiazepines
Yazarlar (5)
Prof. Dr. Meliha Burcu GÜRDERE Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Osman Nuri Aslan Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Yakup BUDAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Mustafa CEYLAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | SYNTHETIC COMMUNICATIONS (Q4) | ||
| Dergi ISSN | 0039-7911 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 46 / 6 / 536–545 | DOI | 10.1080/00397911.2016.1152585 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.1080/00397911.2016.1152585 | ||
| Özet |
| The triethylamin-mediated addition of 2-aminoethanethiol hydrochloride to chalcone analogs was investigated. This addition, bearing a 2-thienyl group at the 3-position, gave the only addition adduct at room temperature in 3 h, whereas the chalcones bearing the 2-furyl group at the 1-position gave an addition-cyclization product (1, 4-thiazepine) in the same conditions. The effect of the groups to the reaction was investigated by changing the 1- and 3-position groups. The chalcones bearing the 2-thienyl group at the 1-position and the others afforded the mixture of products in different ratio at rt for 0.5–24 h. Moreover, the addition–cyclization products (1,4-thiazepine) were obtained under reflux conditions in 36 h. The structures of the synthesized compounds were elucidated by 1H NMR, 13C NMR, infrared, and elemental analysis. |
| Anahtar Kelimeler |
| 2-Aminoethanethiol hydrochloride | chalcones | 1 | 4-thiazephines | triethylamin |
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| Atıf Sayıları | |
| Google Scholar | 9 |
| Web of Science | 6 |