The synthesis and screening of the antimicrobial activity of some novel 3 furan 2 yl 1 aryl 3 phenylthio propan 1 one derivatives
  
Yazarlar (4)
Prof. Dr. Mustafa CEYLAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Meliha Burcu GÜRDERE Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İsa Karaman Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Hayreddin Gezegen Cumhuriyet Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı MEDICINAL CHEMISTRY RESEARCH (Q4)
Dergi ISSN 1054-2523 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2011
Cilt / Sayı / Sayfa 20 / 1 / 109–115 DOI 10.1007/s00044-009-9279-4
Makale Linki http://link.springer.com/10.1007/s00044-009-9279-4
Özet
A series of thiophenol adducts (3a–m) were prepared by addition of thiophenol to chalcones (1a–m) in the presence of a catalytic amount of KOt-Bu in solvent free conditions. In addition, the antibacterial and antifungal in vitro properties were tested against some human pathogenic microorganisms by employing the disk diffusion technique. A majority of compounds were remarkably active against several of the microorganisms. Compound 3i was determined to be the most active compound.
Anahtar Kelimeler
Thiophenol | Chalcones | Antimicrobial activity