Comparison of inflammation markers in different severities of COVID-19 disease
Yazarlar (5)
Doç. Dr. Muzaffer KATAR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Rıza ÇITIL
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Osman DEMİR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
|
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
| Dergi Adı | International Journal of Medical Biochemistry |
| Dergi ISSN | 2587-2362 Scopus Dergi |
| Dergi Tarandığı Indeksler | ProQuest |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2022 |
| Cilt No | 5 |
| Sayı | 1 |
| Sayfalar | 34 / 43 |
| DOI Numarası | 10.14744/ijmb.2021.39358 |
| Makale Linki | https://jag.journalagent.com/ijmb/pdfs/IJMB-39358-ORIGINAL_INVESTIGATION-KATAR.pdf |
| Özet |
| Objectives: We retrospectively analyzed COVID-19 patients for clinical and hematologic features and tried to define the most appropriate markers to diagnose and predict the severity. Methods: This is a retrospective cross-sectional study. All 4443 patients included were diagnosed with reverse trancription-polymerase chain reaction between January 1 and December 30, 2020. We classified patients according to their mode of treatment: outpatient, inpatient in the ward, or inpatients in the intensive care unit (ICU). Results: The mean age of 2283 (51.4%) women and 2160 (48.6%) men included in the study was determined to be 39.77±17.30. Of the 4443 patients, 3985 (89.7%) were outpatients, 330 (7.4%) were inpatients, and 128 (2.9%) patients were treated in the ICU. The mean hospital stay was 8.36±4.55 days for the survivors in the ward group and 2.67±1.53 days for those who died (p=0.031). The mean hospitalization time of the survivors in the ICU group was 19.97±12.09 days, and the mean hospitalization time of the deceased was 13.10±9.99 days (p=0.001). Age, ferritin, D-dimer, glucose, ALT, AST, urea, creatinine, CRP, HgA1c, IMG, IMG%, and RDW-SD showed a gradual and significant increase in outpatient, ward, and ICU groups (p<0.001). Na, K, Neu, Neu%, MCV, RDW-CV, MPV, NLR, PLR, and NMR increased gradually from the outpatient group to the service and ICU groups, whereas Ca, RBC, Hgb, and Hct values decreased significantly (p<0.001). WBC, lymph%, and RDW were highest in the ICU group. Conclusion: Advanced age and being male are important risk factors for hospitalization. Indexes such as NLR, PLR, LCR, NMR, and LMR can be used to predict the severity of the disease |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |