Prevalence of Proteinuria in School-Aged Turkish Children, and Its Association with Obesity and Hypertension     
Yazarlar (11)
Prof. Dr. Ali GÜL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Samet Özer
Türkiye
Resul Yılmaz
Selçuk Üniversitesi, Türkiye
Ergün Sönmezgöz
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Tuba KASAP Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Şahin Takcı
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Nafia Özlem Kazancı
Başkent Üniversitesi, Türkiye
Şeyma Ünüvar
Türkiye
Yalçın Önder
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Rıza ÇITIL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İlknur Bütün
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayınlanan tam makale
Dergi Adı JOURNAL OF PEDIATRIC RESEARCH
Dergi ISSN 2147-9445 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler ESCI: Emerging Sources Citation Index
Makale Dili İngilizce
Basım Tarihi 12-2017
Cilt No 4
Sayı 4
Sayfalar 195 / 199
DOI Numarası 10.4274/jpr.36449
Makale Linki http://cms.galenos.com.tr/Uploads/Article_16510/JPR-4-4.pdf
Özet
Aim In kidney diseases, renal damage may be mild and initially asymptomatic. Proteinuria, a marker of kidney injury, directly contributes to chronic tubulointerstitial damage. We investigated the prevalence of proteinuria (POP) in school-aged children in Turkey. Materials and Methods The cluster sampling method was used to calculate the required size of the study group for this cross-sectional study. Urine samples were randomly obtained to determine urinary protein/creatinine ratio (Upr/Ucr) from 1374 children aged 6 to 18 years. POP was also specifically assessed in hypertensive and obese children. Results The mean age of the subjects was 11.68 +/- 3.43 years. The children were from rural (23.9%) and urban (76.1%) regions of Tokat, Turkey. Upr/Ucr >= 0.20 was detected in 92 children, corresponding to a POP rate of 6.7%, without any statistically significant difference between girls and boys. Among 141 obese children, 16 (11.3%) and 76 of 1233 non-obese children (6.2%) had proteinuria (p<0.05). Children with hypertension had a POP of 7.5% compared to the 6.7% of those without hypertension (p>0.05). Conclusion Among school-aged Turkish children POP was 6.7%. POP was higher in obese than in non-obese children. But there was no association between POP and hypertension. While screening programs allow the early detection of renal disease, further cohort studies are required to be able to suggest urinary screening programs.
Anahtar Kelimeler
Proteinuria | children | obesity | protein creatinine ratio | hypertension