Comparison of the osteogenic differentiation capacity of adipose tissuederived mesenchymal stem cells from humans and rats      
Yazarlar (4)
Doç. Dr. Seçil ERDEN TAYHAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Şeyma Taşdemir
Ege Üniversitesi, Türkiye
Saime İsmet Deliloğlu Gürhan
Ege Üniversitesi, Türkiye
Erol Mir
Manisa Celâl Bayar Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale
Dergi Adı Turkish Journal of Biology
Dergi ISSN 1300-0152 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce
Basım Tarihi 01-2016
Cilt No 40
Sayı 5
Sayfalar 1090 / 1095
DOI Numarası 10.3906/biy-1507-128
Makale Linki http://dx.doi.org/10.3906/biy-1507-128
Özet
Mesenchymal stem cells (MSCs) can be found in many types of adult tissues such as the bone marrow, adipose, placenta, liver, and periosteum. Recently, adipose tissue-derived MSCs (ADMSCs) have become one the most preferred MSC types because of their fast proliferation rate, abundance, and high plasticity for variable cell types. It is known that ADMSCs are able to differentiate into various cells, including osteoblasts, so they are quite promising for orthopedic clinical trials. The present study aimed to compare the osteogenic differentiation conditions of MSCs from human adipose tissue (hADMSC) and those of MSCs from rat adipose tissue (rADMSC). Therefore, differentiation experiments with five different media and two (human and rat) ADMSC types were performed and the mineralization responses of hADMSCs and rADMSCs were different.
Anahtar Kelimeler
Osteogenic differentiation | mesenchymal stem cell | adipose tissue | human | rat