Synthesis and In Vitro Antımıcrobıal Actıvıty of Novel 2 3 Oxo 1 3 diarylpropylthio Acetic Acid Derivatives
Yazarlar (4)
Cumhuriyet Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Mustafa CEYLAN
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | ACTA POLONIAE PHARMACEUTICA |
| Dergi ISSN | 0001-6837 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 09-2012 |
| Cilt No | 69 |
| Sayı | 5 |
| Sayfalar | 893 / 900 |
| Makale Linki | Acta Poloniae Pharmaceutica -Drug Research |
| Özet |
| A series of novel 2-(3-oxo-1,3-diarylpropylthio)acetic acid derivatives (3a-l) were prepared by base catalyzed addition of thioglycolic acid to chalcones (1a-l). The antibacterial activities of synthesized compounds were screened against human pathogenic microorganisms by employing the disk-diffusion technique. For the active compounds, also minimum inhibitory concentrations (MICs) were determined. |
| Anahtar Kelimeler |
| thioglycolic acid | chalcone | Michael addition | antibacterial and antifungal activity |
