Association between sequence variations of the Mediterranean fever gene and fibromyalgia syndrome in a cohort of Turkish patients
Yazarlar (6)
Doç. Dr. Nevin KARAKUŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Serbulent Yigit Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ahmet İNANIR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Sema Inanir Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Huriye Toprak Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Sevil OKAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Clinica Chimica Acta (Q4) | ||
| Dergi ISSN | 0009-8981 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2012 |
| Cilt / Sayı / Sayfa | 414 / 1 / 36–40 | DOI | 10.1016/j.cca.2012.07.019 |
| Özet |
| OBJECTIVE Fibromyalgia syndrome (FMS) is a common chronic widespread pain syndrome mainly affecting women. Genetic risk factors are known to contribute to the etiology of the syndrome. Clinical features show that FMS and familial Mediterranean fever (FMF) have some overlapping symptoms. Mediterranean fever (MEFV) gene has already been identified as being responsible for FMF. The aim of this study was to explore the frequency and clinical significance of missense mutations and a common polymorphism of MEFV gene in a cohort of Turkish patients with FMS. METHODS The study included 187 patients with FMS and 190 healthy controls. Genomic DNA was isolated and genotyped using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analyses for the five MEFV gene mutations (M694V, M680I, V726A, E148Q and P369S) and one polymorphism (R202Q … |
| Anahtar Kelimeler |
| Fibromyalgia | MEFV gene mutation | R202Q |
Science Direct
Association between sequence variations of the Mediterranean fever gene and fibromyalgia syndrome in a cohort of Turkish patients
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 21 |
| Scopus | 1 |
| Web of Science | 15 |