Branch Selective Synthesis of Oxindole and Indene Scaffolds Transition Metal Controlled Intramolecular Aryl Amidation Leading to C3 Reverse Prenylated Oxindoles
Yazarlar (3)
Case Western Reserve University, Amerika Birleşik Devletleri
Prof. Dr. Nihal DELİGÖNÜL
Case Western Reserve University, Amerika Birleşik Devletleri
Case Western Reserve University, Amerika Birleşik Devletleri
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Organic Letters |
| Dergi ISSN | 1523-7060 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2010 |
| Cilt No | 12 |
| Sayı | 16 |
| Sayfalar | 3594 / 3597 |
| DOI Numarası | 10.1021/ol1012372 |
| Makale Linki | http://pubs.acs.org/doi/abs/10.1021/ol1012372 |
| Özet |
| In an effort to access biologically important scaffolds, a concise branch-selective synthesis of C3 tertiary oxindoles by Cu(I)-catalyzed aryl amidation and 2,2-dimethyl indene by Pd(0)-catalyzed Heck cyclization has been accomplished from acyclic reverse-prenylated intermediates. Oxindole C3-enolate generation using NaH followed by alkylation in the presence of appropriate electrophiles provides a novel route to quaternary C3 reverse-prenylated oxindoles. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 31 |
| SCOPUS | 33 |
| Google Scholar | 41 |
| Google Scholar | 41 |