Analysis of estrogen and progesterone receptor gene polymorphisms in leiomyoma
Yazarlar (10)
Muhammed Toprak
Prof. Dr. Hacı Ömer ATEŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Asker Zeki ÖZSOY Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Nihan BOZKURT Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Saime Sezer Sondaş Türkiye
Hatice Yılmaz Doğru
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İlhan Bahri Delibaş
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fazlı DEMİRTÜRK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Muhammed Toprak
Türkiye
Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
|
||
| Dergi Adı | JOURNAL OF CLINICAL LABORATORY ANALYSIS | ||
| Dergi ISSN | 0887-8013 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2019 |
| Cilt / Sayı / Sayfa | 33 / 3 / – | DOI | 10.1002/jcla.22704 |
| Makale Linki | http://doi.wiley.com/10.1002/jcla.22704 | ||
| Özet |
| Background Leiomyoma, one of the most common benign tumors, causes morbidity during the reproductive years in women. The molecular pathogenesis of the disease is not clear. Leiomyomas are hormone‐sensitive tumors affecting around 20%‐25% of women. Gene polymorphism studies could be important and explaining in the evaluation of multifactorial diseases such as leiomyoma. Polymorphisms involving genes responsible for the synthesis and signalization of steroid hormones could be used as genetic markers for hormone‐related conditions. The purpose of this study was to analyze the effect of ERα‐351 XbaI A/G, ERα‐397 PvuII T/C, and progesterone receptor (PGR) PROGINS polymorphisms on the development of leiomyomas. Material and Methods In this study, 213 samples (103 leiomyoma patients and 110 healthy controls) participated. The ERα‐351 XbaI A/G and ERα‐397 PvuII T/C gene … |
| Anahtar Kelimeler |
| estrogen | gene polymorphism | leiomyoma | PCR | progesterone receptor |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 15 |
| Web of Science | 5 |