Antioxidant activity of an anatolian herbal tea—Origanum minutiflorum : isolation and characterization of its secondary metabolites    
Yazarlar (6)
Mahfuz Elmastas
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Süleyman Muhammed Celik
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Nusret GENÇ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Hüseyin Aksit
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ramazan Erenler
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İlhami Gulcin
Atatürk Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı International Journal of Food Properties
Dergi ISSN 1094-2912 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 04-2018
Cilt No 21
Sayı 1
Sayfalar 374 / 384
DOI Numarası 10.1080/10942912.2017.1416399
Makale Linki https://www.tandfonline.com/doi/full/10.1080/10942912.2017.1416399
Özet
Origanum species are significant aromatic and medicinal plants used in food and pharmaceutical industries. Isolation of bioactive compounds was executed on n-butanol extract to yield the compounds responsible for the activities. Tricosan-1-ol (1), (8E,16E)-tetracosa-8,16-diene-1,24-diol (2), azepan-2-one (3), 3,4-dihy-droxybenzoic acid (4), apigenin (5), eriodictyol (6), globoidnan-A (7), luteolin (8), rosmarinic acid (9), apigenin-7-O-glucuronide (10), and vicenin-2 (11) were isolated by chromatographic methods (column chromatography and semi-pre-parative High Performance Liquid Chromatography (HPLC) and structures were elucidated on the basis of spectroscopic techniques including 1D/2D nuclear magnetic resonance (NMR) and Liquid chromatography/Time-of-flight/Mass spectrometry (LC-TOF/MS). The isolated compounds and extracts were applied for antioxidant assays including 1,1-diphenyl-2-picrylhydrazyl (DPPH•) scavenging, 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS•+) scavenging, reducing power, and cuprac techniques. 3,4-Dihydroxy benzoic acid (4), eriodictyol (6), luteolin (8), and rosmarinic acid (9) revealed the considerable antioxidant activities.
Anahtar Kelimeler
Antioxidant activity | Chromatography | Herbal tea | Origanum minutiflorum | Spectroscopy