The relationship between radial artery spasm and adropin levels in patients undergoing transradial coronary angiography       
Yazarlar (9)
Fuat Bice
Türkiye
Mehmet Eyüboğlu
Türkiye
Doç. Dr. Zeliha Cansel ÖZMEN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Barış Açıkel
Türkiye
Mustafa Yılmaz
Dr. Öğr. Üyesi Metin KARAYAKALI Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Kayıhan KARAMAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Çağrı ZORLU Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayınlanan tam makale
Dergi Adı JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH
Dergi ISSN 2008-5117 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler ESCI
Makale Dili İngilizce
Basım Tarihi 06-2022
Cilt No 14
Sayı 2
Sayfalar 90 / 94
DOI Numarası 10.34172/jcvtr.2022.15
Makale Linki http://dx.doi.org/10.34172/jcvtr.2022.15
Özet
Introduction: Transradial coronary angiography (TRA) is associated with a lower incidence of bleeding rate and access site complications and is associated with better outcomes compared to transfemoral angiography. However, radial artery spasm (RAS) is an important limitation of TRA procedures. Little is known regarding the relationship of serum vasodilator and inflammatory markers with RAS. Therefore, the present study aimed to investigate the association between serum adropin level and RAS in patients undergoing TRA. Methods: From February 2020 to January 2021, 39 consecutive patients who underwent elective daiagnostic TRA and experienced RAS during the procedure, and 42 age and sex matched controls who did not experience RAS were prospectively included into the study. The groups were compared regarding serum adropin levels and inflammatory markers. Results: Although adropin levels were found to be lower in the RAS group, this difference was not statistically significant between the the patients with RAS and controls (14.9 vs. 16.1, P= 0.105). However, inflammatory parameters monocyte count and MHR (monocyte/HDL cholesterol ratio) were found to be statistically significantly higher in the RAS group compared to controls (P= 0.001 and P= 0.010, respectively). Moreover, a significant positive correlation was found between the monocyte count and RAS (r:0.360, P< 0.001), and between MHR and RAS (r:0.288, P= 0.009). Furthermore, multivariate analysis demonstrated that monocyte count (OR:1.671, 95%CI:1.312-2.094, P= 0.001) and MHR (OR:1.116, 95%CI:1.054-1.448, P= 0.022) were found to be independent predictors of RAS. Conclusion: Serum vasodilator and inflammatory markers may be useful in the prediction of RAS in patients undergoing TRA procedures.
Anahtar Kelimeler
Adropin | Coronary Artery Disease | Monocyte Count | Monocyte/HDL Cholesterol | Radial Artery Vasospasm | Ratio | Transradial Coronary Angiography